Caulimoviridae Tubule-Guided Transport Is Dictated by Movement Protein Properties

Caulimoviridae tubule-guided transport is dictated by movement protein properties.

Plant viruses move through plasmodesmata (PD) either as nucleoprotein complexes (NPCs) or as tubule-guided encapsidated particles with the help of movement proteins (MPs). To explore how and why MPs specialize in one mechanism or the other, we tested the exchangeability of MPs encoded by DNA and RNA virus genomes by means of an engineered alfalfa mosaic virus (AMV) system. We show that Caulimov...

How movement is guided

The development of a theory of prospective guidance of movement general tau theory is described. The theory deals with the purposive guidance of bodily movements, including internal movements, by means of the patterns of flow in sensory arrays and the patterns of flow of electrical energy within the nervous system. The central idea is that movement is guided by tau-coupling action-gaps. All pur...

Medical practice is actually dictated by lawyers.

Tubule-Guided Cell-to-Cell Movement of a Plant Virus Requires Class XI Myosin Motors

Cell-to-cell movement of plant viruses occurs via plasmodesmata (PD), organelles that evolved to facilitate intercellular communications. Viral movement proteins (MP) modify PD to allow passage of the virus particles or nucleoproteins. This passage occurs via several distinct mechanisms one of which is MP-dependent formation of the tubules that traverse PD and provide a conduit for virion trans...

F-Box Protein Specificity for G1 Cyclins Is Dictated by Subcellular Localization

Levels of G1 cyclins fluctuate in response to environmental cues and couple mitotic signaling to cell cycle entry. The G1 cyclin Cln3 is a key regulator of cell size and cell cycle entry in budding yeast. Cln3 degradation is essential for proper cell cycle control; however, the mechanisms that control Cln3 degradation are largely unknown. Here we show that two SCF ubiquitin ligases, SCF(Cdc4) a...